- January 1: A Day in the Park with Barney was permanently closed at Universal Orlando Resort due to the COVID-19 pandemic and the age of the attraction.
- February 24: During Mattel's 2021 Virtual Analyst Day Presentation, Barney was included to be a "new series in development" by Mattel Television.
- November 15: A three-part documentary about Barney the Dinosaur is announced to be in the works by streaming service Peacock. Produced by Scout Productions, the documentary is announced for a 2022 release.
- April 22: Originally scheduled to release in 2020, Toy Factory, LLC, a company that distributes plush toys for amusement parks, attractions, family entertainment centers, and vending machines, lists the Barney & Friends, 3 Asst. on their website, which features new plush versions of Barney, BJ, and Baby Bop. The plush toys were later distributed to where Toy Factory, LLC distributes their plush toys in the year.
- July 23: Spirit Halloween, an annual pop-up costume store, lists an officially licensed Adult Barney Inflatable Costume product on their website. Although listed on the date, the product didn't become available for retailers and online purchase until mid-September.
- March 24: Announcement of Barney & Friends added to 'Kids & Family' on The Roku Channel, with only Seasons ten and eleven available to stream initially. Season twelve became available at a later date.
- March 25: Streaming service Tubi has announced they entered into a content deal with 9 Story Media Group to obtain one year of exclusive streaming rights to Seasons seven through nine of Barney & Friends, as well as non-exclusive streaming rights to seasons ten to twelve. The episodes became available to stream on April 9, 2021.
- May 1: Seasons thirteen and fourteen of Barney & Friends become available to stream on the streaming service Netflix,  making it the first time since 2017 the franchise is added to the streaming service.
- August 10: Free streaming service XUMO announced that it expanded its Kids TV channel with more content including featuring Barney & Friends, only showcasing Seasons ten, eleven, and twelve.
- September 23: Barney & Friends becomes available to stream on Kidoodle.TV, only showcasing Season eleven.
- October 25: New York-based studio and streamer FilmRise announced they licensed a slate of classic children’s shows for its North American AVoD platform FilmRise Streaming Network, including Barney & Friends, announcing they're showcasing Seasons ten to fourteen. They have been acquired in non-exclusive deals with 9 Story Media Group.
- October 29: Barney & Friends becomes available to stream on Peacock, showcasing Seasons ten, eleven, and twelve.
- November 5: Barney & Friends becomes available to stream on Kidstream, only showcasing Season ten.
- December: Tubi adds Seasons thirteen and fourteen of Barney & Friends.
- January 24 - Jeanne Cairns (actress)
- February 12 - Phyllis Cicero (actress)
- April 3 - Mark Elliott (voice-over artist)
- On October 27, Barney was trending on Twitter due to a user posting a PBS Kids shows Tier List and putting Barney & Friends all the way on the bottom. Users on Twitter came to the show's defense.
- CONFIRMED: A Day in the Park with Barney at Universal Studios Florida is Permanently Closed
- 2021 Mattel (Virtual) Analyst Day Presentation | Barbie, Monster High, Polly Pocket | Dolls Category
- | Barney the Dinosaur Documentary in the Works at Peacock
- New Kids & Family content on The Roku Channel
- Tubi to Stream ‘Barney & Friends’ Beginning April 9
- Tubi Grabs Streaming Rights to 1990s Children’s Hit ‘Barney & Friends’
- TUBI TO BECOME EXCLUSIVE HOME TO THREE SEASONS OF ICONIC CHILDREN’S SERIES BARNEY & FRIENDS BEGINNING APRIL 9
- Netflix May 2021 Movie and TV Titles Announced
- What’s Coming to Netflix in May 2021
- XUMO Adds Garfield, Barney & More to Free Kids TV Lineup
- New on Kidoodle.TV® This Week!
- | FilmRise acquires children’s shows including Barney & Friends, Angelina Ballerina
- | Carbon Dating Web
- Jeanne Hebborn Cairns, 88, actor who defined the role of Sister Clarissa in 'Over the Tavern'
- Today we celebrate and pay homage to Phyllis Cicero
- Mark Elliott, longtime Disney trailer voice actor, dies at 81
- | The Internet Defends Barney The Dinosaur Over Viral Twitter Trend